Type 2 Diabetes Mellitus, A State Of Relative Insulin...

Type 2 diabetes mellitus, a state of relative insulin deficiency with underlying insulin resistance, accounts for majority of the cases of hyperglycemia worldwide. An estimated 422 million people worldwide have diabetes [1], and this number is expected to reach 592 million by the year 2035 [2]. Almost 30 million Americans (9% of the population) have diabetes, with estimated total health care costs of $245 billion due to extensive complications, primarily micro- and macrovascular pathology. Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death among individuals with type 2 diabetes, in whom adverse cardiovascular outcomes occur, on average, 14.6 years earlier [5] and with increased severity compared to individuals without diabetes mellitus. People with type 2 diabetes have twofold-increased risk of developing ASCVD [6]. The increment in the diabetic population with cardiovascular events reflects the steady increase in the number of older individuals in the United States and the improved survival of individuals with diabetes. Prevalence of obesity, which is related to risk for ASCVD and diabetes, is also on an upsurge in the United States as well as globally. Guidelines from the American Heart Association (AHA)/American Diabetes Association (ADA) [7] and the European Society of Cardiology [8] present different recommendations for individuals with diabetes depending on an individual s risk profile. To identify patients who will benefit most fromShow MoreRelatedWhat is Diabetes Mellitus? Essay655 Words   |  3 PagesWhat is Diabetes Mellitus? Diabetes is a very common disorder. It is the 8th leading cause of death worldwide. It is projected that the number of individuals with diabetes will almost double by 2030. 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GDM alsoRead MoreGestational Diabetes Mellitus : An Overview1241 Words   |  5 Pages Gestational Diabetes Mellitus Isaac Anzaldua Norma Beardwood (Roper), MBA, M. Ed., RDN, LD, LPC, CEDS DIET 4252 September 21, 2015 â€Æ' Gestational Diabetes Mellitus Introduction Diabetes Mellitus is a disease; which occurs through the insufficiency of insulin being produced or its actions are not being utilized. This occurrence leads to hyperglycemia; an issue in which the amount of glucose in the blood is relatively high. Gestational Diabetes Mellitus falls under the category of DM. GDM also consistRead MoreDiabetes Mellitus : Long Term Damage1144 Words   |  5 PagesIntroduction The term diabetes mellitus describes a metabolic disorder of multiple aetiology, characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. 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There are two major classifications of diabetes mellitus; insulin-dependent (IDDM) and noninsulin-dependent (NIDDM). IDDM is more commonly known as Type 1 Diabetes, and NIDDM is known as Type 2 Diabetes (EkoeÃŒ , 2008). Type 1 diabetes is the juvenile-onset diabetes that deals with the complete destruction of ÃŽ ²-cells of the pancreas whereas type 2 diabetes is an adult-onset disorder in which individuals suffer from an insulin deficiencyRead MoreDiabetes Mellitus Type 2: A Research1511 Words   |  6 Pagesa serious metabolic disorder called Diabetes Mellitus Type 2. While not managed by insulin injections, it is nevertheless quite serious and has a number of progressing symptoms that, if not treated properly, can result in cardiovascular, renal and neurological problems, as well as amputation, ocular is sues, and even cognitive dysfunction. Type II Diabetes, also known as diabetes mellitus, is also called non-insulin-dependent diabetes or aadult onset diabetes. It is a medical disorder that, due to